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DLE may refer to:
- An ISO 269 envelope size
- Discoid lupus erythematosus, a chronic skin condition
- Data Link Escape, one of the C0 and C1 control codes
- DLE (company), a Japanese animation studio
- The IATA code for Dole–Jura Airport, France
- Dry Low Emission, an emission reduction technology used in gas turbines
- District Level Examination, basic level final examination in Nepal
| disambiguation page lists articles associated with the title DLE.
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