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Distal-less homeobox 6
Symbols DLX6 ; MGC125282; MGC125283; MGC125284; MGC125285
External IDs OMIM600030 HomoloGene87855 GeneCards: DLX6 Gene
RNA expression pattern
PBB GE DLX6 221289 at tn.png
More reference expression data
Species Human Mouse
Entrez 1750 13396
Ensembl ENSG00000006377 ENSMUSG00000029754
UniProt P56179 P70397
RefSeq (mRNA) NM_005222 NM_010057
RefSeq (protein) NP_005213 NP_034187
Location (UCSC) Chr 7:
97.01 – 97.01 Mb
Chr 6:
6.86 – 6.87 Mb
PubMed search [1] [2]

Homeobox protein DLX-6 is a protein that in humans is encoded by the DLX6 gene.[1][2]

This gene encodes a member of a homeobox transcription factor gene family similar to the Drosophila distal-less gene. This family has at least six members that encode proteins with roles in forebrain and craniofacial development. This gene is in a tail-to-tail configuration with another member of the family on the long arm of chromosome 7.[2]


  1. ^ Simeone A, Acampora D, Pannese M, D'Esposito M, Stornaiuolo A, Gulisano M, Mallamaci A, Kastury K, Druck T, Huebner K; et al. (Apr 1994). "Cloning and characterization of two members of the vertebrate Dlx gene family". Proc Natl Acad Sci U S A 91 (6): 2250–4. doi:10.1073/pnas.91.6.2250. PMC 43348. PMID 7907794. 
  2. ^ a b "Entrez Gene: DLX6 distal-less homeobox 6". 

Further reading[edit]