DMSA scan

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DMSA scan
Medical diagnostics
DMSA scan while on enalapril.jpg
Decreased Tc99m-DMSA uptake in both kidneys, suggestive of renal failure.
OPS-301 code3-706.0

A DMSA scan is a radionuclide scan that uses dimercaptosuccinic acid (DMSA) in assessing renal morphology, structure and function. Radioactive technetium-99m is combined with DMSA and injected into a patient, followed by imaging with a gamma camera.[1] A DMSA scan is usually static, other radiotracers are usually used with dynamic imaging to assess renal function.[2]

The major clinical indications for this investigation are the detection and/or evaluation of a renal scar, the small or absent kidney (renal agenesis), an occult duplex system, certain renal masses, systemic hypertension or suspected vasculitis.[3] It is sometimes used as a test for the diagnosis of acute pyelonephritis.[4] However, the sensitivity of DMSA scan for acute pyelonephritis may be as low as 46%.[5]


  1. ^ "Renal Cortical Scintigraphy (DMSA scan) Clinical Guidelines" (PDF). BNMS. 2011. Retrieved 11 June 2017.
  2. ^ Fogelman, Ignac; Clarke, Susan; Cook, Gary; Gnanasegaran, Gopinath (2014). Atlas of Clinical Nuclear Medicine, Third Edition. CRC Press. p. 443. ISBN 9781841847528.
  3. ^ Gordon I (March 1987). "Indications for 99mtechnetium dimercapto-succinic acid scan in children". The Journal of Urology. 137 (3): 464–7. PMID 3029435.
  4. ^ Goldraich NP, Goldraich IH (April 1995). "Update on dimercaptosuccinic acid renal scanning in children with urinary tract infection". Pediatric Nephrology. 9 (2): 221–6, discussion 227. doi:10.1007/bf00860755. PMID 7794724.
  5. ^ Bailey RR, Lynn KL, Robson RA, Smith AH, Maling TMJ, Turner JG. "DMSA renal scans in adults with acute pyelonephritis". Clinical Nephrology. 46 (2): 99–104. PMID 8869786.

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