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DnaJ (Hsp40) homolog, subfamily B, member 1
Protein DNAJB1 PDB 1hdj.png
PDB rendering based on 1hdj.
Available structures
PDB Ortholog search: PDBe, RCSB
Symbols DNAJB1 ; HSPF1; Hdj1; Hsp40; RSPH16B; Sis1
External IDs OMIM604572 MGI1931874 HomoloGene55957 GeneCards: DNAJB1 Gene
RNA expression pattern
PBB GE DNAJB1 200666 s at tn.png
PBB GE DNAJB1 200664 s at tn.png
More reference expression data
Species Human Mouse
Entrez 3337 81489
Ensembl ENSG00000132002 ENSMUSG00000005483
UniProt P25685 Q9QYJ3
RefSeq (mRNA) NM_001300914 NM_001308227
RefSeq (protein) NP_001287843 NP_001295156
Location (UCSC) Chr 19:
14.51 – 14.53 Mb
Chr 8:
83.61 – 83.61 Mb
PubMed search [1] [2]

DnaJ homolog subfamily B member 1 is a protein that in humans is encoded by the DNAJB1 gene.[1][2][3]


DNAJB1 has been shown to interact with:


  1. ^ Hata M, Okumura K, Seto M, Ohtsuka K (Mar 1997). "Genomic cloning of a human heat shock protein 40 (Hsp40) gene (HSPF1) and its chromosomal localization to 19p13.2". Genomics 38 (3): 446–9. doi:10.1006/geno.1996.0653. PMID 8975727. 
  2. ^ Ohtsuka K (Jan 1994). "Cloning of a cDNA for heat-shock protein hsp40, a human homologue of bacterial DnaJ". Biochem Biophys Res Commun 197 (1): 235–40. doi:10.1006/bbrc.1993.2466. PMID 8250930. 
  3. ^ "Entrez Gene: DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1". 
  4. ^ Oh WK, Song J (Aug 2003). "Cooperative interaction of Hsp40 and TPR1 with Hsp70 reverses Hsp70-HspBp1 complex formation". Mol. Cells 16 (1): 84–91. PMID 14503850. 
  5. ^ Ballinger CA, Connell P, Wu Y, Hu Z, Thompson LJ, Yin LY, Patterson C (Jun 1999). "Identification of CHIP, a novel tetratricopeptide repeat-containing protein that interacts with heat shock proteins and negatively regulates chaperone functions". Mol. Cell. Biol. 19 (6): 4535–45. doi:10.1128/mcb.19.6.4535. PMC 104411. PMID 10330192. 

Further reading[edit]