|Privately held company|
DNASTAR is a global bioinformatics software company incorporated in 1984 that is headquartered in Madison, Wisconsin. DNASTAR develops and sells software for sequence analysis in the fields of genomics, molecular biology, and structural biology.
DNASTAR software (Lasergene) first gained popularity in the 1980s and 1990s for its sequence assembly and analysis capabilities of Sanger sequencing data. Lasergene 15.2 was released in June 2018. DNASTAR software is available for desktop computers running Mac OS X, Windows, and Linux as well as for use on Amazon Web Services.
In 2007, DNASTAR expanded their offerings to include software for next-generation sequencing and structural biology. DNASTAR's next-gen software supports data from Illumina, Ion Torrent, and Pacific Biosciences and allows the user to assemble, align, analyze and visualize genomic data. Lasergene's use in next-generation sequence assembly and analysis was contributed as a chapter, written by company scientists, to the 2008 book Next Generation Genome Sequencing edited by Michael Janitz.
Writing in The Scientist, David R. Smith gave positive reviews to several bioinformatics software packages including DNAstar, but said that his bioinformatics skills plateaued and the licensing and upgrading costs were a significant proportion of his lab's operating budget.
The 2008 book Inventing Entrepreneurs: Technology Innovators and their Entrepreneurial Journey by Gerard George and Adam J. Bock includes DNASTAR as an example of an innovative and entrepreneurial success story.
A research study by BMC Genomics in 2010 determined that SeqMan (DNASTAR's next-gen sequence assembly application) assemblies performed best, with more novel sequences and better recapitulation of transcripts.
Another BMC Genomics study in 2011 determined that the best overall contig performance resulted from a SeqMan NGen assembly.
- "Lasergene 15.2 Release Notes | DNASTAR". DNASTAR. 2018-06-26. Retrieved 2018-10-08.
- "Company Profile". DNASTAR. Retrieved 25 October 2014.[self-published source]
- Janitz, Michael (November 2008). Next-Generation Genome Sequencing: Towards Personalized Medicine. Wiley-VCH. ISBN 978-3-527-32090-5.
- "DNASTAR Careers". DNASTAR. Retrieved 25 October 2014.[self-published source]
- The Scientist, September 2, 2014 http://www.the-scientist.com/?articles.view/articleNo/40916/title/Opinion--Bioinformatics-Software--A-Buyer-s-Guide/
- Staff (30 June 2007). "Bioinformatics Readers' Choice — Gold Award: Lasergene". Product Releases. Scientific Computing. Advantage Business Media.
- Gerry, George; Bock, Adam (January 2008). Inventing Entrepreneurs: Technology Innovators and their Entrepreneurial Journey. Prentice Hall. ISBN 978-0-13-157470-0.[page needed]
- Kumar, Sujai; Blaxter, Mark L. (16 October 2010). "Comparing de novo assemblers for 454 transcriptome data". BMC Genomics. 11: 571. doi:10.1186/1471-2164-11-571. PMC 3091720. PMID 20950480. 571.
- Feldmeyer, Barbara; Wheat, Christopher W.; et al. (16 June 2011). "Short read Illumina data for the de novo assembly of a non-model snail species transcriptome (Radix balthica, Basommatophora, Pulmonata), and a comparison of assembler performance". BMC Genomics. 12: 317. doi:10.1186/1471-2164-12-317. PMC 3128070. PMID 21679424. 317.
- Staff (1 January 2014). "Products & Services Deals". Gen. Eng. Biotechnol. News (paper)
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...entered into a multiyear software license agreement with DNAStar for the use of Lasergene software as its primary sequence assembly and analysis software platform for researchers within its organization.
- Schwei, Tom (2 March 2017). "DNASTAR Releases Lasergene 14.1 Software With Major Enhancements" (Press release). DNASTAR.[self-published source]