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DNA damage-binding protein

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damage-specific DNA binding protein 1, 127kDa
Identifiers
SymbolDDB1
Alt. symbolsXPE
NCBI gene1642
HGNC2717
OMIM600045
RefSeqNM_001923
UniProtQ16531
Other data
LocusChr. 11 q12-q13
Search for
StructuresSwiss-model
DomainsInterPro
damage-specific DNA binding protein 2, 48kDa
Identifiers
SymbolDDB2
Alt. symbolsDBB, UV-DDB2, FLJ34321
NCBI gene1643
HGNC2718
OMIM600811
RefSeqNM_000107
UniProtQ92466
Other data
LocusChr. 11 p12-p11
Search for
StructuresSwiss-model
DomainsInterPro

DNA damage-binding protein is a protein complex that is responsible for repair of UV-damaged DNA.[1] This complex is composed of two protein subunits, a large subunit DDB1 and a small subunit DDB2. This complex functions in nucleotide excision repair.

References

  1. ^ Dualan R, Brody T, Keeney S, Nichols AF, Admon A, Linn S (Feb 1996). "Chromosomal localization and cDNA cloning of the genes (DDB1 and DDB2) for the p127 and p48 subunits of a human damage-specific DNA binding protein". Genomics. 29 (1): 62–9. doi:10.1006/geno.1995.1215. PMID 8530102.{{cite journal}}: CS1 maint: multiple names: authors list (link)