DNM3

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DNM3
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesDNM3, Dyna III, dynamin 3
External IDsMGI: 1341299 HomoloGene: 22906 GeneCards: DNM3
Gene location (Human)
Chromosome 1 (human)
Chr.Chromosome 1 (human)[1]
Chromosome 1 (human)
Genomic location for DNM3
Genomic location for DNM3
Band1q24.3Start171,841,498 bp[1]
End172,418,466 bp[1]
RNA expression pattern
PBB GE DNM3 209839 at fs.png
More reference expression data
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001038619
NM_172646

RefSeq (protein)

NP_001033708
NP_766234

Location (UCSC)Chr 1: 171.84 – 172.42 MbChr 1: 161.98 – 162.48 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Dynamin-3 is a protein that in humans is encoded by the DNM3 gene.[5][6] The protein encoded by this gene is a member of the dynamin family which possess mechanochemical properties involved in actin-membrane processes, predominantly in membrane budding.[7] DNM3 is upregulated in Sézary's syndrome.[8]

References[edit]

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000197959 - Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000040265 - Ensembl, May 2017
  3. ^ "Human PubMed Reference:".
  4. ^ "Mouse PubMed Reference:".
  5. ^ Nagase T, Ishikawa K, Suyama M, Kikuno R, Hirosawa M, Miyajima N, Tanaka A, Kotani H, Nomura N, Ohara O (May 1999). "Prediction of the coding sequences of unidentified human genes. XII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro". DNA Res. 5 (6): 355–64. doi:10.1093/dnares/5.6.355. PMID 10048485.
  6. ^ "Entrez Gene: DNM3 dynamin 3".
  7. ^ Orth JD, McNiven MA (February 2003). "Dynamin at the actin-membrane interface". Curr. Opin. Cell Biol. 15 (1): 31–9. doi:10.1016/S0955-0674(02)00010-8. PMID 12517701.
  8. ^ Booken N, Gratchev A, Utikal J, Weiss C, Yu X, Qadoumi M, Schmuth M, Sepp N, Nashan D, Rass K, Tüting T, Assaf C, Dippel E, Stadler R, Klemke CD, Goerdt S (February 2008). "Sézary syndrome is a unique cutaneous T-cell lymphoma as identified by an expanded gene signature including diagnostic marker molecules CDO1 and DNM3". Leukemia. 22 (2): 393–9. doi:10.1038/sj.leu.2405044. PMID 18033314.

Further reading[edit]