DNM3

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DNM3
Available structures
PDB Ortholog search: PDBe RCSB
Identifiers
Aliases DNM3, Dyna III, dynamin 3
External IDs MGI: 1341299 HomoloGene: 22906 GeneCards: 26052
RNA expression pattern
PBB GE DNM3 209839 at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001136127
NM_001278252
NM_015569

NM_001038619
NM_172646

RefSeq (protein)

NP_001129599.1
NP_001265181.1
NP_056384.2

NP_001033708.1
NP_766234.1

Location (UCSC) Chr 1: 171.84 – 172.42 Mb Chr 1: 161.98 – 162.48 Mb
PubMed search [1] [2]
Wikidata
View/Edit Human View/Edit Mouse

Dynamin-3 is a protein that in humans is encoded by the DNM3 gene.[1][2] The protein encoded by this gene is a member of the dynamin family which possess mechanochemical properties involved in actin-membrane processes, predominantly in membrane budding.[3] DNM3 is upregulated in Sézary's syndrome.[4]

References[edit]

  1. ^ Nagase T, Ishikawa K, Suyama M, Kikuno R, Hirosawa M, Miyajima N, Tanaka A, Kotani H, Nomura N, Ohara O (May 1999). "Prediction of the coding sequences of unidentified human genes. XII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro". DNA Res 5 (6): 355–64. doi:10.1093/dnares/5.6.355. PMID 10048485. 
  2. ^ "Entrez Gene: DNM3 dynamin 3". 
  3. ^ Orth JD, McNiven MA (February 2003). "Dynamin at the actin-membrane interface". Curr. Opin. Cell Biol. 15 (1): 31–9. doi:10.1016/S0955-0674(02)00010-8. PMID 12517701. 
  4. ^ Booken N, Gratchev A, Utikal J, Weiss C, Yu X, Qadoumi M, Schmuth M, Sepp N, Nashan D, Rass K, Tüting T, Assaf C, Dippel E, Stadler R, Klemke CD, Goerdt S (February 2008). "Sézary syndrome is a unique cutaneous T-cell lymphoma as identified by an expanded gene signature including diagnostic marker molecules CDO1 and DNM3". Leukemia 22 (2): 393–9. doi:10.1038/sj.leu.2405044. PMID 18033314. 

Further reading[edit]