DPYSL2

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DPYSL2
Protein DPYSL2 PDB 2gse.png
Available structures
PDB Ortholog search: PDBe RCSB
Identifiers
Aliases DPYSL2, CRMP-2, CRMP2, DHPRP2, DRP-2, DRP2, N2A3, ULIP-2, ULIP2, dihydropyrimidinase like 2
External IDs MGI: 1349763 HomoloGene: 74392 GeneCards: 1808
RNA expression pattern
PBB GE DPYSL2 200762 at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001386
NM_001197293
NM_001244604

NM_009955

RefSeq (protein)

NP_001184222.1
NP_001231533.1
NP_001377.1

NP_034085.2

Location (UCSC) Chr 8: 26.51 – 26.66 Mb Chr 14: 66.8 – 66.87 Mb
PubMed search [1] [2]
Wikidata
View/Edit Human View/Edit Mouse

Dihydropyrimidinase-related protein 2 is an enzyme that in humans is encoded by the DPYSL2 gene.[1][2]


Interactions[edit]

DPYSL2 has been shown to interact with CRMP1,[3] Adaptor-related protein complex 2, alpha 1[4] and NUMB.[4]

References[edit]

  1. ^ Hamajima N, Matsuda K, Sakata S, Tamaki N, Sasaki M, Nonaka M (Jan 1997). "A novel gene family defined by human dihydropyrimidinase and three related proteins with differential tissue distribution". Gene 180 (1–2): 157–63. doi:10.1016/S0378-1119(96)00445-3. PMID 8973361. 
  2. ^ "Entrez Gene: DPYSL2 dihydropyrimidinase-like 2". 
  3. ^ Leung, Thomas; Ng Yvonne; Cheong Albert; Ng Chong Han; Tan Ivan; Hall Christine; Lim Louis (Dec 2002). "p80 ROKalpha binding protein is a novel splice variant of CRMP-1 which associates with CRMP-2 and modulates RhoA-induced neuronal morphology". FEBS Lett. (Netherlands) 532 (3): 445–9. doi:10.1016/S0014-5793(02)03736-5. ISSN 0014-5793. PMID 12482610. 
  4. ^ a b Nishimura, Takashi; Fukata Yuko; Kato Katsuhiro; Yamaguchi Tomoya; Matsuura Yoshiharu; Kamiguchi Hiroyuki; Kaibuchi Kozo (Sep 2003). "CRMP-2 regulates polarized Numb-mediated endocytosis for axon growth". Nat. Cell Biol. (England) 5 (9): 819–26. doi:10.1038/ncb1039. ISSN 1465-7392. PMID 12942088. 

Further reading[edit]