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DR5 may refer to:

  • DR5 (car), an Italian Mini SUV by DR Motor Company, based on the Chinese SUV Chery Tiggo
  • TNFRSF10B, a human gene
  • dr5 chrome, a reversal black-and-white process
  • DR-5, a highway in the Dominican Republic
  • DR5 register, a debug register in x86 processors