DYNC1I1

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DYNC1I1
Identifiers
Aliases DYNC1I1, dynein, cytoplasmic 1, intermediate chain 1, DNCI1, DNCIC1, dynein cytoplasmic 1 intermediate chain 1
External IDs MGI: 107743 HomoloGene: 68398 GeneCards: DYNC1I1
Genetically Related Diseases
obesity, smallpox[1]
RNA expression pattern
PBB GE DYNC1I1 205348 s at fs.png
More reference expression data
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001135556
NM_001135557
NM_001278421
NM_001278422
NM_004411

NM_001191023
NM_001191025
NM_001191026
NM_001191027
NM_010063

RefSeq (protein)

NP_001129028
NP_001129029
NP_001265350
NP_001265351
NP_004402

Location (UCSC) Chr 7: 95.77 – 96.11 Mb Chr 6: 5.73 – 6.03 Mb
PubMed search [2] [3]
Wikidata
View/Edit Human View/Edit Mouse

Cytoplasmic dynein 1 intermediate chain 1 is a protein that in humans is encoded by the DYNC1I1 gene.[4][5][6]

In melanocytic cells DYNC1I1 gene expression may be regulated by MITF.[7]


Interactions[edit]

DYNC1I1 has been shown to interact with DYNLL1.[8]

References[edit]

  1. ^ "Diseases that are genetically associated with DYNC1I1 view/edit references on wikidata". 
  2. ^ "Human PubMed Reference:". 
  3. ^ "Mouse PubMed Reference:". 
  4. ^ Crackower MA, Sinasac DS, Xia J, Motoyama J, Prochazka M, Rommens JM, Scherer SW, Tsui LC (May 1999). "Cloning and characterization of two cytoplasmic dynein intermediate chain genes in mouse and human". Genomics. 55 (3): 257–67. doi:10.1006/geno.1998.5665. PMID 10049579. 
  5. ^ Pfister KK, Fisher EM, Gibbons IR, Hays TS, Holzbaur EL, McIntosh JR, Porter ME, Schroer TA, Vaughan KT, Witman GB, King SM, Vallee RB (Nov 2005). "Cytoplasmic dynein nomenclature". J Cell Biol. 171 (3): 411–3. doi:10.1083/jcb.200508078. PMC 2171247Freely accessible. PMID 16260502. 
  6. ^ "Entrez Gene: DYNC1I1 dynein, cytoplasmic 1, intermediate chain 1". 
  7. ^ Hoek KS, Schlegel NC, Eichhoff OM, et al. (2008). "Novel MITF targets identified using a two-step DNA microarray strategy". Pigment Cell Melanoma Res. 21 (6): 665–76. doi:10.1111/j.1755-148X.2008.00505.x. PMID 19067971. 
  8. ^ Diefenbach, Russell J; Diefenbach Eve; Douglas Mark W; Cunningham Anthony L (Dec 2002). "The heavy chain of conventional kinesin interacts with the SNARE proteins SNAP25 and SNAP23". Biochemistry. United States. 41 (50): 14906–15. doi:10.1021/bi026417u. ISSN 0006-2960. PMID 12475239. 

Further reading[edit]