DYNLT1

From Wikipedia, the free encyclopedia
Jump to: navigation, search
DYNLT1
Identifiers
Aliases DYNLT1, CW-1, TCTEL1, tctex-1, dynein light chain Tctex-type 1
External IDs MGI: 98643 HomoloGene: 4754 GeneCards: 6993
RNA expression pattern
PBB GE DYNLT1 201999 s at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_006519
NM_001291602
NM_001291603

NM_009342

RefSeq (protein)

NP_006510.1

NP_001160099.1
NP_001160101.1
NP_001160102.1
NP_033368.1

Location (UCSC) Chr 6: 158.64 – 158.64 Mb Chr 17: 6.43 – 6.44 Mb
PubMed search [1] [2]
Wikidata
View/Edit Human View/Edit Mouse

Dynein light chain Tctex-type 1 is a protein that in humans is encoded by the DYNLT1 gene.[1][2][3]

Cytoplasmic dynein is the major motor protein complex responsible for minus-end, microtubule-based motile processes. Each dynein complex consists of 2 heavy chains that have ATPase and motor activities, plus a group of accessory polypeptides. TCTEX1 is a dynein light chain involved in cargo binding (Chuang et al., 2005).[supplied by OMIM][3]

References[edit]

  1. ^ Watanabe TK, Fujiwara T, Shimizu F, Okuno S, Suzuki M, Takahashi E, Nakamura Y, Hirai Y (Jul 1996). "Cloning, expression, and mapping of TCTEL1, a putative human homologue of murine Tcte1, to 6q". Cytogenet Cell Genet 73 (1-2): 153–6. doi:10.1159/000134329. PMID 8646886. 
  2. ^ Pfister KK, Fisher EM, Gibbons IR, Hays TS, Holzbaur EL, McIntosh JR, Porter ME, Schroer TA, Vaughan KT, Witman GB, King SM, Vallee RB (Nov 2005). "Cytoplasmic dynein nomenclature". J Cell Biol 171 (3): 411–3. doi:10.1083/jcb.200508078. PMC 2171247. PMID 16260502. 
  3. ^ a b "Entrez Gene: DYNLT1 dynein, light chain, Tctex-type 1". 

Further reading[edit]