DYNLT1

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DYNLT1
Identifiers
Aliases DYNLT1, CW-1, TCTEL1, tctex-1, dynein light chain Tctex-type 1
External IDs MGI: 3807476 HomoloGene: 4754 GeneCards: DYNLT1
Gene location (Human)
Chromosome 6 (human)
Chr. Chromosome 6 (human)[1]
Chromosome 6 (human)
Genomic location for DYNLT1
Genomic location for DYNLT1
Band 6q25.3 Start 158,636,474 bp[1]
End 158,644,739 bp[1]
RNA expression pattern
PBB GE DYNLT1 201999 s at fs.png
More reference expression data
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_006519
NM_001291602
NM_001291603

NM_001166630

RefSeq (protein)

NP_001278531
NP_001278532
NP_006510

NP_001160099
NP_001186877
NP_001160101
NP_001160102
NP_033368

Location (UCSC) Chr 6: 158.64 – 158.64 Mb Chr 6: 6.6 – 6.61 Mb
PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Dynein light chain Tctex-type 1 is a protein that in humans is encoded by the DYNLT1 gene.[5][6][7]

Cytoplasmic dynein is the major motor protein complex responsible for minus-end, microtubule-based motile processes. Each dynein complex consists of 2 heavy chains that have ATPase and motor activities, plus a group of accessory polypeptides. TCTEX1 is a dynein light chain involved in cargo binding (Chuang et al., 2005).[supplied by OMIM][7]

References[edit]

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000146425 - Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000000579 - Ensembl, May 2017
  3. ^ "Human PubMed Reference:". 
  4. ^ "Mouse PubMed Reference:". 
  5. ^ Watanabe TK, Fujiwara T, Shimizu F, Okuno S, Suzuki M, Takahashi E, Nakamura Y, Hirai Y (Jul 1996). "Cloning, expression, and mapping of TCTEL1, a putative human homologue of murine Tcte1, to 6q". Cytogenet Cell Genet. 73 (1-2): 153–6. doi:10.1159/000134329. PMID 8646886. 
  6. ^ Pfister KK, Fisher EM, Gibbons IR, Hays TS, Holzbaur EL, McIntosh JR, Porter ME, Schroer TA, Vaughan KT, Witman GB, King SM, Vallee RB (Nov 2005). "Cytoplasmic dynein nomenclature". J Cell Biol. 171 (3): 411–3. doi:10.1083/jcb.200508078. PMC 2171247Freely accessible. PMID 16260502. 
  7. ^ a b "Entrez Gene: DYNLT1 dynein, light chain, Tctex-type 1". 

Further reading[edit]