Damnacanthal

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Damnacanthal
Chemical structure of damnacanthal
Names
IUPAC name
3-Hydroxy-1-methoxy-9,10-dioxoanthracene-2-carbaldehyde
Other names
3-Hydroxy-1-methoxyanthraquinone-2-aldehyde
Identifiers
3D model (Jmol)
ChemSpider
ECHA InfoCard 100.208.625
Properties
C16H10O5
Molar mass 282.25 g·mol−1
Density 1.461 g/mL
Boiling point 532 °C (990 °F; 805 K)
Related compounds
Related arylformaldehydes
Gossypol

Pyridoxal

Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Infobox references

Damnacanthal is an anthraquinone which acts as a p56lck tyrosine kinase inhibitor.[1] It can be extracted from Morinda citrifolia.[2]

References[edit]

  1. ^ Faltynek CR, Schroeder J, Mauvais P, et al. (September 1995). "Damnacanthal is a highly potent, selective inhibitor of p56lck tyrosine kinase activity". Biochemistry. 34 (38): 12404–10. doi:10.1021/bi00038a038. PMID 7547985. 
  2. ^ Anekpankul T, Goto M, Sasaki M, et al. (July 2007). "Extraction of anti-cancer damnacanthal from roots of Morinda citrifolia by subcritical water". Separation and Purification Technology. 55 (3): 343–349. doi:10.1016/j.seppur.2007.01.004.