Damnacanthal

Damnacanthal
Names
	IUPAC name 3-Hydroxy-1-methoxy-9,10-dioxoanthracene-2-carbaldehyde
	Other names 3-Hydroxy-1-methoxyanthraquinone-2-aldehyde
Identifiers
CAS Number	477-84-9
ChEMBL	ChEMBL212948
ChemSpider	2843
Jmol 3D model	Interactive image
PubChem	2948
	InChI InChI=1S/C16H10O5/c1-21-16-11(7-17)12(18)6-10-13(16)15(20)9-5-3-2-4-8(9)14(10)19/h2-7,18H,1H3 Key: IPDMWUNUULAXLU-UHFFFAOYSA-N ; InChI=1S/C16H10O5/c1-21-16-11(7-17)12(18)6-10-13(16)15(20)9-5-3-2-4-8(9)14(10)19/h2-7,18H,1H3 ;
	SMILES COC1=C2C(=CC(=C1C=O)O)C(=O)C3=CC=CC=C3C2=O ;
Properties
Chemical formula	C16H10O5
Molar mass	282.25 g·mol−1
Density	1.461 g/mL
Boiling point	532 °C (990 °F; 805 K)
Related compounds
Related arylformaldehydes	Gossypol; Pyridoxal
	Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
	verify (what is ?)
	Infobox references

Damnacanthal is an anthraquinone which acts as a p56lck tyrosine kinase inhibitor.^[1] It can be extracted from Morinda citrifolia.^[2]

References[edit]

^ Faltynek CR, Schroeder J, Mauvais P, et al. (September 1995). "Damnacanthal is a highly potent, selective inhibitor of p56lck tyrosine kinase activity". Biochemistry 34 (38): 12404–10. doi:10.1021/bi00038a038. PMID 7547985.
^ Anekpankul T, Goto M, Sasaki M, et al. (July 2007). "Extraction of anti-cancer damnacanthal from roots of Morinda citrifolia by subcritical water". Separation and Purification Technology 55 (3): 343–349. doi:10.1016/j.seppur.2007.01.004.

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