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Dampier Highway, formerly known as Karratha-Dampier Road, is a Western Australian highway linking Dampier on the state's north-western coast with the nearby regional centre of Karratha and North West Coastal Highway. The road is 39 kilometres (24 mi) long.
Its terminus is at the intersection of Central Avenue and Church Road in Dampier.
The road was completed in the late 1960s as a major link between Karratha and Dampier.
Duplication of Dampier Highway between Balmoral Road West and Burrup Peninsula Road, turning it into a dual carriageway, was completed on 28 February 2013.