David Goeddel

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David V. Goeddel (born 1951) is an American biotechnology worker who, employed at the time by Genentech, successfully used genetic engineering to coax bacteria into creating synthetic human insulin, human growth hormone, and human tissue plasminogen activator (tPA) for use in therapeutic medicine. By contrast, the pharmaceutical industries had been researching synthetically created versions of those proteins.

Recruited by Bob Swanson in 1978, he was the first non-university scientist to be hired[1] at Genentech, and the company's third employee.[1] Goeddel became legendary in the biotechnology and molecular biology fields by cloning virtually all of Genentech's early products and/or processes, including synthetic insulin, growth hormone, and tPA, often beating out bigger and more established laboratories in the process. Besides being perhaps the single most important contributor to Genentech's rise to one of the nation's premier biotech companies, his extraordinary drive and competitive work ethic embodied Genentech's early "Clone or Die" culture[2]

Together with Steve McKnight and Robert Tjian, he founded Tularik in 1991, and was their president and CEO until Tularik was acquired by Amgen for $1.3 billion in 2004.[3]

Goeddel earned his bachelor's degree in chemistry from the University of California, San Diego, and his PhD from the University of Colorado, Boulder. He is a member of the National Academy of Sciences, and is a recipient of the Eli Lilly Award in Biological Chemistry and the Scheele Award from the Swedish Academy of Pharmaceutical Sciences.

Personal life[edit]

Goeddel has two sons who are active Major League Baseball players, Erik and Tyler.[4]

The brothers are now in the Los Angeles Dodgers system (as of 5/18/18).


  1. ^ a b Eric W. Pfeiffer (1999-05-31). "Biotechnology All-Stars". Forbes. 
  2. ^ Invisible Frontiers: The Race to Synthesize a Human Gene by Stephen S. Hall (1987, Tempus Books of Microsoft Press)
  3. ^ Amgen (2004-03-29). "Amgen to Acquire Tularik for $1.3 Billion". Amgen. 
  4. ^ http://www.philly.com/philly/sports/phillies/20160715_Goeddel_brothers_to_finally_meet_when_Phillies_host_the_Mets_this_weekend.html