Delanterone

From Wikipedia, the free encyclopedia
Jump to: navigation, search
Delanterone
Delanterone.svg
Identifiers
Synonyms GBR-21162
CAS Number 63014-96-0
PubChem (CID) 205969
ChemSpider 178468
UNII AM2KZ47R0J
ChEMBL CHEMBL2104221
Chemical and physical data
Formula C20H28O
Molar mass 284.43572 g/mol
3D model (Jmol) Interactive image

Delanterone (INN) (developmental code name GBR-21162), also known as 1α-methylandrosta-4,16-dien-3-one, is a steroidal antiandrogen described as an anti-acne agent which was never marketed.[1][2][3] The compound showed poor efficacy as an antiandrogen in vivo in animals, suggestive of low activity or a short half-life, and likely in relation to this was not further developed.[3] It was characterized and reported on in 1977.[1][3]

See also[edit]

References[edit]

  1. ^ a b J. Elks (14 November 2014). The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies. Springer. pp. 794–. ISBN 978-1-4757-2085-3. 
  2. ^ Martin Negwer; Hans-Georg Scharnow (2001). Organic-chemical drugs and their synonyms: (an international survey). Wiley-VCH. ISBN 978-3-527-30247-5. 
  3. ^ a b c Singh, Shankar; Gauthier, Sylvain; Labrie, Fernand (2000). "Androgen Receptor Antagonists (Antiandrogens) Structure-Activity Relationships". Current Medicinal Chemistry. 7 (2): 211–247. doi:10.2174/0929867003375371. ISSN 0929-8673.