Delta1-piperideine-2-carboxylate reductase

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delta1-piperideine-2-carboxylate reductase
Identifiers
EC number1.5.1.21
CAS number52037-88-4
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO

In enzymology, a Delta1-piperideine-2-carboxylate reductase (EC 1.5.1.21) is an enzyme that catalyzes the chemical reaction

L-pipecolate + NADP+ Delta1-piperideine-2-carboxylate + NADPH + H+

Thus, the two substrates of this enzyme are L-pipecolate and NADP+, whereas its 3 products are Delta1-piperideine-2-carboxylate, NADPH, and H+.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-NH group of donors with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is L-pipecolate:NADP+ 2-oxidoreductase. Other names in common use include 1,2-didehydropipecolate reductase, P2C reductase, and 1,2-didehydropipecolic reductase. This enzyme participates in lysine degradation.

References[edit]

  • Payton CW, Chang YF (1982). "delta1-piperideine-2-carboxylate reductase of Pseudomonas putida". J. Bacteriol. 149 (3): 864–71. PMC 216472. PMID 6801013.