Demecarium bromide

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Demecarium bromide
Demecarium bromide.svg
Clinical data
Trade names Humorsol
Routes of
Topical (ophthalmic solution)
ATC code S01EB04 (WHO)
CAS Number 56-94-0 YesY
PubChem (CID) 5965
DrugBank DB00944 YesY
ChemSpider 5750 YesY
KEGG D00667 YesY
ECHA InfoCard 100.000.274
Chemical and physical data
Formula C32H52Br2N4O4
Molar mass 716.588 g/mol
3D model (Jmol) Interactive image
 NYesY (what is this?)  (verify)

Demecarium bromide is a parasympathomimetic that acts as an acetylcholinesterase inhibitor. It is one of several topical (applied directly to the affected area) medications used to reduce elevated intraocular pressure (IOP) associated with primary glaucoma in cats, dogs, and other animals.[1][2][3]

See also[edit]


  1. ^ Ward D, Abney K, Oliver J (2003). "The effects of topical ocular application of 0.25% demecarium bromide on serum acetylcholinesterase levels in normal dogs.". Vet Ophthalmol. 6 (1): 23–5. doi:10.1046/j.1463-5224.2003.00257.x. PMID 12641839. 
  2. ^ Krohne S (1994). "Effect of topically applied 2% pilocarpine and 0.25% demecarium bromide on blood-aqueous barrier permeability in dogs.". Am J Vet Res. 55 (12): 1729–33. PMID 7887518. 
  3. ^ Gum G, Gelatt K, Gelatt J, Jones R (1993). "Effect of topically applied demecarium bromide and echothiophate iodide on intraocular pressure and pupil size in beagles with normotensive eyes and beagles with inherited glaucoma.". Am J Vet Res. 54 (2): 287–93. PMID 8430939.