With Rory McGrath and Jimmy Mulville, she co-founded the independent British TV production company Hat Trick Productions in 1986. As a television producer, O'Donoghue has worked on shows such as the Original, British, version of Whose Line is it Anyway?, and Have I Got News for You. McGrath left the company in 1992.
O'Donoghue married Mulville in 1987. They divorced in the mid-nineties but continued to work together. In 2006 she married Michael Holland, a multi-millionaire oil shipping businessman, whose wife, Jane Attenborough, 49 (daughter of Richard Attenborough), his 15-year-old daughter Lucy, and his mother, Jane Holland, 83, had all drowned in the tsunami in December 2004. He founded Oil Aid, which has raised millions for charities.
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