Dense irregular connective tissue

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Illustration of Dense Irregular Connective Tissue (Deep Dermis)

Dense irregular connective tissue has fibers that are not arranged in parallel bundles as in dense regular connective tissue.

Dense irregular connective tissue consists of mostly collagen fibers. Fibroblasts are prodominant cell type scattered sparsely across the tissue. [1] This tissue relative to loose connective tissue contains smaller portion of ground substance. [2]


This type connective tissue is found mostly in reticular layer (or deep layer) of the dermis[3] This type of tissue is also in the Sclera and in the deeper skin layers. Due to high portions of collagenous fibers, dense irregular connective tissue provides strength, making the skin resistant to tearing as consequence of stretching forces from different directions.[4]

It also makes up submucosa of the digestive tract, fibrous capsules of joints and lymph nodes, and some types of fascia.[5] Other examples include periosteum and perichondrium and tunica albugenia. In the submucosa layer, the fiber bundles course in varying planes allowing the organ to resist excessive stretching and distension.


  1. ^ "Connective Tissue". Archived from the original on 2008-11-07. Retrieved 2008-11-27. 
  2. ^ Mescher, Anthony L. (2013). Junqueira's basic histology : text & atlas (13th [rev.] ed.). New York [etc.]: McGraw-Hill Medical. ISBN 978-0-07-180798-2. 
  3. ^
  4. ^ Pawlina, Wojciech (2016). Histology: A Text and Atlas: With Correlated Cell and Molecular Biology 7th Edition. China: J. B. Lippincott. pp. 158–159. ISBN 978-1451187427. 
  5. ^