Phillips started his radio career in 1949 on WHBQ/560 in Memphis with a special studio at the Gayoso Hotel. His nightly radio program, "Red, Hot & Blue," appeared on the WHBQ schedule for the first time the night of November 3, 1949, in the 10:15 - 11:00 pm slot. In 1953 WHBQ moved to the mezzanine floor of the Chisca Hotel. Dewey Phillips was the city's leading radio personality for nine years and was the first to simulcast his "Red, Hot & Blue" show on radio and television. During the 1950s he had 100,000 listeners to his 9pm-midnight slot and he received 3,000 letters a week.
Phillips' on-air persona was a speed-crazed hillbilly, with a frantic delivery and entertaining sense of humor. He also had a keen ear for music the listening public would enjoy, and he aired both black and white music, which was abundant in post-World War II Memphis, a booming river city which attracted large numbers of rural blacks and whites (along with their musical traditions). Dr. W. Herbert Brewster, pastor of East Trigg Baptist Church, was a frequent guest on Dewey's program. He played a great deal of rhythm and blues, country music, boogie-woogie, and jazz as well as Sun Records artists. In 1950, Phillips and his friend Sam Phillips (no relation) decided to launch their own record label. Joe Hill Louis waxed an electric blues single, "Boogie in the Park" (recorded in July 1950 and released the following month). It was the only record released on the Phillips label before Sam founded Sun Records.
In July 1954, he was the first DJ to broadcast the young Elvis Presley's debut record, "That's All Right" / "Blue Moon Of Kentucky" (Sun 209), and got Presley to reveal his race in an interview by asking which high school the 19-year-old singer attended (knowing that, because of segregation, his audience would readily know what race attended which schools).
Dewey Phillips was bringing Black Music to segregated Memphis before Alan Freed did the same as Moon Dog in Cleveland. Phillips briefly hosted an afternoon program on WHBQ-TV/13 in the mid-1950s, before Dick Clark took over Philadelphia Bandstand then American Bandstand on WFIL-TV. It mostly consisted of Phillips playing records while he and others clowned around in front of the camera.
Though Phillips was not involved in the payola scandals of the time (as was Freed), he was fired in late 1958 when the station adopted a Top 40 format, phasing out his freeform style. He had Sam Phillips and three other friends, Wink Martindale, T.L. Meade, and Sonny Gilmore to bail him out and keep him steady as work and recognition faded. He spent the last decade of his life working at smaller radio stations, seldom lasting long. The popular musical Memphis is said to be based loosely on Dewey Phillips' life and career, although elements crucial in the career of Phillips' contemporary Alan Freed appear to be intermixed as well.
- "American RadioWorks - Hearing America: A Century of Music on the Radio". Americanradioworks.publicradio.org. Retrieved 26 January 2019.
- "Today's Radio Programs and Highlights". The Commercial Appeal. November 3, 1949. p. 35. Retrieved January 31, 2022.
- Cantor, Louis. Dewey and Elvis: The Life and Times of a Rock 'n' Roll Deejay. Urbana, Ill: University of Illinois Press, 2005.
- Robert Palmer (1981). Deep Blues. Penguin Books. p. 228. ISBN 978-0-14-006223-6.
- DeCurtis, Anthony (1992). Present Tense: Rock & Roll and Culture (4th ed.). Durham, N.C.: Duke University Press. ISBN 0822312654.
His first venture, the Phillips label, issued only one known release, and it was one of the loudest, most overdriven, and distorted guitar stomps ever recorded, 'Boogie in the Park' by Memphis one-man-band Joe Hill Louis, who cranked his guitar while sitting and banging at a rudimentary drum kit.
- Gilliland, John (1969). "Show 7 - The All American Boy: Enter Elvis and the rock-a-billies. [Part 1]" (audio). Pop Chronicles. University of North Texas Libraries.
- "Dewey Phillips and Elvis Presley - Elvis Articles". Elvis.com.au. Retrieved 26 January 2019.
- "Wink Martindale on meeting Elvis Presley - TelevisionAcademy.com/Interviews". YouTube. Archived from the original on 2021-12-19. Retrieved 26 January 2019.
- "BC Bryan Fenkart". Bryan Fenkart. VOA Music. Archived from the original on 2021-12-19.
- "'Memphis' Headed to Broadway Theaters". Archived from the original on 2009-03-14. Retrieved 2009-03-10.
- Cantor (2005) p.31
- Dewey Phillips resting place at Find a Grave
- "Rockabilly Hall of Fame: Dewey Phillips". Rockabillyhall.com. Retrieved 26 January 2019.
- "Louis Cantor / Dewey and Elvis". 8 March 2006. Archived from the original on 8 March 2006. Retrieved 26 January 2019.
- "Q magazine, July 2000 issue". Biwa.ne.jp. Retrieved 26 January 2019.
- One hour of airchecks, 1952-1960s. Broadcast August 14, 2002.
- Photo of Phillips at Find a Grave