Dexbrompheniramine

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Dexbrompheniramine
Dexbrompheniramine.svg
Clinical data
Trade names Drixoril, Conex, Dixaphedrine
AHFS/Drugs.com Multum Consumer Information
Pregnancy
category
  • US: C (Risk not ruled out)
Routes of
administration
Oral
ATC code
Legal status
Legal status
Pharmacokinetic data
Biological half-life 25 hours
Identifiers
CAS Number
PubChem CID
IUPHAR/BPS
DrugBank
ChemSpider
UNII
ChEBI
ChEMBL
ECHA InfoCard 100.004.595
Chemical and physical data
Formula C16H19BrN2
Molar mass 319.24 g/mol
3D model (Jmol)
 NYesY (what is this?)  (verify)

Dexbrompheniramine is an antihistamine with anticholinergic properties[1] used to treat allergic conditions such as hay fever or urticaria. It is the pharmacologically active dextrorotatory isomer of brompheniramine. It was formerly marketed in combination with pseudoephedrine under the name Drixoral in the US and Canada.

Dexbrompheniramine is a first generation antihistamine that reduces the effects of natural chemical histamine in the body; sneezing, itching, watery eyes, and runny nose.

Interactions[edit]

MAO inhibitors within 14 days. MAO inhibitors include isocarboxazid, linezolid, phenelzine, rasagiline, selegiline, and tranylcypromine.

Potassium (Cytra, Epiklor, K-Lyte, K-Phos, Kaon, Klor-Con, Polycitra, Urocit-K).

Drinking alcohol can increase side effects of dexbrompheniramine.

References[edit]

  1. ^ Löfkvist, T. (1978). "A comparative evaluation of oral decongestants in the treatment of vasomotor rhinitis". The Journal of international medical research. 6 (1): 56–60. PMID 627306.