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Dextranomer (trade name Debrisan, Exudex) is a cicatrizant used in dressings for wound healing, and in pharmaceutical products to treat fecal incontinence. It consists of dextran polymer chains cross-linked into a three-dimensional network.
Solesta is the marketed brand name of a system of injections of dextranomer in stabilized sodium hyaluronate for use in fecal incontinence (FI). This preparation is a biocompatible gel, for use as a perianal injectable bulking agent. The system is intended to be injected in the submucosal layer of the proximal anal canal (i.e. above the level of the dentate line).
- "Establishment Registration & Device Listing".
- Parulkar BG, Sobti MK, Pardanani DS (1985). "Dextranomer dressing in the treatment of infected wounds and cutaneous ulcers". J Postgrad Med. 31 (1): 28–33.
- "Solesta Gel Approved for Fecal Incontinence - Drugs.com MedNews".
- Solesta Package Insert
- Hoy, SM (Aug 20, 2012). "Dextranomer in stabilized sodium hyaluronate (Solesta): in adults with faecal incontinence.". Drugs. 72 (12): 1671–8. doi:10.2165/11209030-000000000-00000. PMID 22845415.
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