Dextranomer

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Dextranomer
Dextranomer skeletal.svg
Clinical data
Trade names Debrisan
AHFS/Drugs.com International Drug Names
Routes of
administration
Topical
ATC code
Identifiers
CAS Number
PubChem SID
ChemSpider
  • none
ECHA InfoCard 100.128.106
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Dextranomer (trade name Debrisan, Exudex[1]) is a cicatrizant used in dressings for wound healing,[2] and in pharmaceutical products to treat fecal incontinence.[3] It consists of dextran polymer chains cross-linked into a three-dimensional network.[4]

Solesta[edit]

Solesta is the marketed brand name of a system of injections of dextranomer in stabilized sodium hyaluronate for use in fecal incontinence (FI).[5] This preparation is a biocompatible gel, for use as a perianal injectable bulking agent. The system is intended to be injected in the submucosal layer of the proximal anal canal (i.e. above the level of the dentate line).

References[edit]

  1. ^ "Establishment Registration & Device Listing". 
  2. ^ Parulkar BG, Sobti MK, Pardanani DS (1985). "Dextranomer dressing in the treatment of infected wounds and cutaneous ulcers". J Postgrad Med. 31 (1): 28–33. 
  3. ^ "Solesta Gel Approved for Fecal Incontinence - Drugs.com MedNews". 
  4. ^ Solesta Package Insert
  5. ^ Hoy, SM (Aug 20, 2012). "Dextranomer in stabilized sodium hyaluronate (Solesta): in adults with faecal incontinence.". Drugs. 72 (12): 1671–8. doi:10.2165/11209030-000000000-00000. PMID 22845415. 

External links[edit]