Diaminopropionate ammonia-lyase

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diaminopropionate ammonia-lyase
Identifiers
EC number 4.3.1.15
CAS number 51901-19-0
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum
Gene Ontology AmiGO / QuickGO

In enzymology, a diaminopropionate ammonia-lyase (EC 4.3.1.15) is an enzyme that catalyzes the chemical reaction

2,3-diaminopropanoate + H2O pyruvate + 2 NH3

Thus, the two substrates of this enzyme are 2,3-diaminopropionate and H2O, whereas its two products are pyruvate and NH3.

This enzyme belongs to the family of lyases, specifically ammonia lyases, which cleave carbon-nitrogen bonds. The systematic name of this enzyme class is 2,3-diaminopropanoate ammonia-lyase (adding H2O; pyruvate-forming). Other names in common use include diaminopropionatase, alpha,beta-diaminopropionate ammonia-lyase, 2,3-diaminopropionate ammonia-lyase, and 2,3-diaminopropanoate ammonia-lyase. It employs one cofactor, pyridoxal phosphate.

References[edit]

  • Nagasawa T, Tanizawa K, Satoda T, Yamada H (1988). "Diaminopropionate ammonia-lyase from Salmonella typhimurium Purification and characterization of the crystalline enzyme, and sequence determination of the pyridoxal 5'-phosphate binding peptide". J. Biol. Chem. 263 (2): 958–64. PMID 3275662.