Dibutylchloromethyltin chloride

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Dibutylchloromethyltin chloride
Dibutylchloromethyltin chloride.svg
Names
IUPAC name
Dibutyl(chloro)(chloromethyl)stannane
Other names
DBCT
Identifiers
3D model (JSmol)
ChemSpider
UNII
  • InChI=1S/2C4H9.CH2Cl.ClH.Sn/c2*1-3-4-2;1-2;;/h2*1,3-4H2,2H3;1H2;1H;/q;;;;+1/p-1
    Key: XWFCEWFXSQFZPI-UHFFFAOYSA-M
  • CCCC[Sn](CCCC)(CCl)Cl
Properties
C9H20Cl2Sn
Molar mass 317.87 g·mol−1
Hazards
Occupational safety and health (OHS/OSH):
Main hazards
Toxic, vesicant
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).

Dibutylchloromethyltin chloride (DBCT) is a toxic organotin compound. It's a potent and irreversible ATP synthase inhibitor.[1][2][3] DBCT is a volatile liquid with powerful vesicant effects.[1]

See also[edit]

References[edit]

  1. ^ a b Cain, K; Partis, MD; Griffiths, DE (15 September 1977). "Dibutylchloromethyltin chloride, a covalent inhibitor of the adenosine triphosphate synthase complex". The Biochemical Journal. 166 (3): 593–602. doi:10.1042/bj1660593. PMC 1165045. PMID 145860.
  2. ^ Moore, Anthony L.; Linnett, Paul E.; Beechey, R. Brian (August 1980). "Dibutylchloromethyltin chloride, a potent inhibitor of electron transport in plant mitochondria". Journal of Bioenergetics and Biomembranes. 12 (3–4): 309–323. doi:10.1007/bf00744691. PMID 7217044. S2CID 29130410.
  3. ^ Diwan, Joyce Johnson (February 1982). "Some effects of dibutylchloromethyltin chloride and other reagents on mitochondrial K+ flux". Journal of Bioenergetics and Biomembranes. 14 (1): 15–22. doi:10.1007/bf00744076. PMID 7142136. S2CID 24153839.