Dicentrine

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Dicentrine
Dicentrine.png
Identifiers
3D model (JSmol)
ChemSpider
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references

Dicentrine is an anticancer compound isolated from Lindera.

S-(+)-Dicentrine is an aporphinic alkaloid found in several plant species, mainly from Lauraceae family, which showed significant antinociceptive activity in an acute model of visceral pain in mice. It has also been shown to reduce spontaneous nociception and attenuating mechanical and cold hypersensitivity, probably via a TRPA1-dependent mechanism.[1]

References[edit]

  1. ^ Montrucchio, Deise Prehs; Córdova, Marina Machado; Santos, Adair Roberto Soares (2013-07-04). "Plant Derived Aporphinic Alkaloid S-(+)-Dicentrine Induces Antinociceptive Effect in Both Acute and Chronic Inflammatory Pain Models: Evidence for a Role of TRPA1 Channels". PLOS ONE. 8 (7): e67730. doi:10.1371/journal.pone.0067730. ISSN 1932-6203. PMC 3701576. PMID 23861794.