Dieter Seebach

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Dieter Seebach
Born (1937-10-31) 31 October 1937 (age 80)
Karlsruhe, Germany
Nationality German
Alma mater University of Karlsruhe (TH)
Harvard University
Awards Marcel Benoist Prize (2000)
The Ryoji Noyori Prize (2004)
Arthur C. Cope Award (2019)
Scientific career
Institutions University of Karlsruhe (TH)
University of Giessen
ETH Zurich
Doctoral advisor Rudolf Criegee
Doctoral students Dieter Enders
Influenced Elias James Corey

Dieter Seebach is a German chemist known for his synthesis of biopolymers and dendrimers, and for his contributions to stereochemistry. He was born on 31 October 1937 in Karlsruhe. He studied chemistry at the University of Karlsruhe (TH) under the supervision of Rudolf Criegee and at Harvard University with Elias Corey finishing in 1969. After his habilitation he became professor for organic chemistry at the University of Giessen. After six years he was appointed professor at the ETH Zurich where he worked until he retired in 2003.


He works on dendrimer chemistry and on the synthesis of beta-peptides.[1][2] The development of the umpolung, a polarity inversion of the carbonyl group, with 1,3-propanedithiol together with Corey had a big influence on organic synthesis.[3]

The Fráter–Seebach alkylation, a diastereoselective reaction of beta-hydroxy esters, is named after him.



  1. ^ Hook, David F. (2004). "Celebrating Dieter Seebach's Contributions to Science: A Bitter Sweet Occasion?". Chimia. 58 (2): 321–324. doi:10.2533/000942904777677876.
  2. ^ Dieter Seebach and Jennifer L. Matthews (1997). "β-Peptides: a surprise at every turn". Chem. Commun. (21): 2015–2022. doi:10.1039/a704933a.
  3. ^ Seebach D., Corey E. J. (1975). "Generation and synthetic applications of 2-lithio-1,3-dithianes". Journal of Organic Chemistry. 40 (2): 231–237. doi:10.1021/jo00890a018.

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