|Molar mass||105.14 g·mol−1|
|Density||1.097 g mL−1|
|Melting point||28.00 °C; 82.40 °F; 301.15 K|
|Boiling point||271.1 °C; 519.9 °F; 544.2 K|
|Vapor pressure||<1 Pa (at 20 °C)|
|UV-vis (λmax)||260 nm|
Refractive index (nD)
|137 J K−1 mol−1|
Std enthalpy of
|−496.4–−491.2 kJ mol−1|
Std enthalpy of
|−26.548–−26.498 MJ kmol−1|
|GHS signal word||DANGER|
|H302, H315, H318, H373|
|R-phrases||R22, R38, R41, R48/22|
|S-phrases||(S2), S26, S36/37/39|
|Flash point||138 °C (280 °F; 411 K)|
|365 °C (689 °F; 638 K)|
LD50 (Lethal dose)
|US health exposure limits (NIOSH):|
Except where noted otherwise, data is given for materials in their standard state (at 25 °C (77 °F), 100 kPa)
|what is: / ?)(|
Diethanolamine, often abbreviated as DEA or DEOA, is an organic compound with the formula HN(CH2CH2OH)2. Pure diethanolamine is a white solid at room temperature, but its tendency to absorb water and to supercool mean it is often encountered as a colorless, viscous liquid. Diethanolamine is polyfunctional, being a secondary amine and a diol. Like other organic amines, diethanolamine acts as a weak base. Reflecting the hydrophilic character of the alcohol groups, DEA is soluble in water. Amides prepared from DEA are often also hydrophilic.
- C2H4O + NH3 → H2NCH2CH2OH
which reacts with a second and third equivalent of ethylene oxide to give DEA and triethanolamine:
- C2H4O + H2NCH2CH2OH → HN(CH2CH2OH)2
- C2H4O + HN(CH2CH2OH)2 → N(CH2CH2OH)3
In oil refineries, a DEA in water solution is commonly used to remove hydrogen sulfide from sour gas. It has an advantage over a similar amine ethanolamine in that a higher concentration may be used for the same corrosion potential. This allows refiners to scrub hydrogen sulfide at a lower circulating amine rate with less overall energy usage.
Commonly used ingredients that may contain DEA
DEA is used in the production of diethanolamides, which are common ingredients in cosmetics and shampoos added to confer a creamy texture and foaming action. Consequently, some cosmetics that include diethanolamides as ingredients may contain traces of DEA. Some of the most commonly used diethanolamides include:
DEA is a potential skin irritant in workers sensitized by exposure to water-based metalworking fluids. One study showed that DEA inhibits in baby mice the absorption of choline, which is necessary for brain development and maintenance; however, a study in humans determined that dermal treatment for 1 month with a commercially available skin lotion containing DEA resulted in DEA levels that were "far below those concentrations associated with perturbed brain development in the mouse". In a mouse study of chronic exposure to inhaled DEA at high concentrations (above 150 mg/m3), DEA was found to induce body and organ weight changes, clinical and histopathological changes, indicative of mild blood, liver, kidney and testicular systemic toxicity. A 2009 study found that DEA has potential acute, chronic and subchronic toxicity properties for aquatic species.
- "NIOSH Pocket Guide to Chemical Hazards". National Institute for Occupational Safety and Health (NIOSH). id=0208.
- "Akzo-Nobel data sheet". Retrieved 2013-08-14.
- Matthias Frauenkron, Johann-Peter M elder, Günther Ruider, Roland Rossbacher, Hartmut Höke “Ethanolamines and Propanolamines” in Ullmann's Encyclopedia of Industrial Chemistry 2002 by Wiley-VCH, Weinheim doi:10.1002/14356007.a10_001
- Klaus Weissermel, Hans-Jürgen Arpe, Charlet R. Lindley, Stephen Hawkins (2003). "Chap. 7. Oxidation Products of Ethylene". Industrial Organic Chemistry. Wiley-VCH. pp. 159–161. ISBN 3-527-30578-5.
- Lessmann H, Uter W, Schnuch A, Geier J (2009). "Skin sensitizing properties of the ethanolamines mono-, di-, and triethanolamine. Data analysis of a multicentre surveillance network (IVDK*) and review of the literature". Contact Dermatitis 60 (5): 243–255. doi:10.1111/j.1600-0536.2009.01506.x. PMID 19397616.
- Study Shows Ingredient Commonly Found In Shampoos May Inhibit Brain Development
- Craciunescu, CN; Niculescu, MD; Guo, Z; Johnson, AR; Fischer, L; Zeisel, SH (2009). "Dose response effects of dermally applied diethanolamine on neurogenesis in fetal mouse hippocampus and potential exposure of humans.". Toxicological sciences : an official journal of the Society of Toxicology 107 (1): 220–6. doi:10.1093/toxsci/kfn227. PMC 2638646. PMID 18948303.
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- Libralato G, Volpi Ghirardini A, Avezzù F (2009). "Seawater ecotoxicity of monoethanolamine, diethanolamine and triethanolamine". J Hazard Mater 176 (1–3): 535–9. doi:10.1016/j.jhazmat.2009.11.062. PMID 20022426.