Diflucortolone valerate

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Diflucortolone valerate
Diflucortolone valerate.svg
Names
IUPAC name
(6α,11β,16α)-6,9-Difluoro-11-hydroxy-16-methyl-3,20-dioxopregna-1,4-dien-21-yl pentanoate
Other names
Afusona; Diflucortolone 21-valerate
Identifiers
3D model (JSmol)
ChEMBL
ChemSpider
ECHA InfoCard 100.056.032
Properties
C27H36F2O5
Molar mass 478.58 g·mol−1
Melting point 220 °C (428 °F; 493 K)[1]
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Infobox references

Diflucortolone valerate (also Nerisone cream/oily cream/ointment, Neriderm ointment, Japanese ジフルコルトロン (Jifurucorutoron) is a corticosteroid rated Class 2 "potent" (100-150 times) in the New Zealand topical steroid system. It is a white to creamy white crystalline powder. It is practically insoluble in water, freely soluble in dichloromethane and in dioxan, sparingly soluble in ether and slightly soluble in methyl alcohol. Chemically, it is a corticosteroid esterified with valeric acid. It is commonly used topically in dermatology. The brand name is Nerisone; its creams come in potencies of 0.1% and 0.3%.

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