Dihydropyrimidine dehydrogenase (NADP+)
|dihydropyrimidine dehydrogenase (NADP+)|
Dihydroprymidine dehydrogenase dimer, Sus scrofa
|PDB structures||RCSB PDB PDBe PDBsum|
|Gene Ontology||AmiGO / QuickGO|
- 5,6-dihydrouracil + NADP+ uracil + NADPH + H+
This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-CH group of donor with NAD+ or NADP+ as acceptor.
The systematic name of this enzyme class is 5,6-dihydrouracil:NADP+ 5-oxidoreductase.
Other names in common use include:
- dihydrothymine dehydrogenase
- dihydrouracil dehydrogenase (NADP+)
- 4,5-dihydrothymine: oxidoreductase
- dehydrogenase, dihydrouracil (nicotinamide adenine dinucleotide, phosphate)
- DHU dehydrogenase
- hydropyrimidine dehydrogenase
- dihydropyrimidine dehydrogenase (NADP+)
- FRITZSON P (1960). "Properties and assay of dihydrouracil dehydrogenase of rat liver". J. Biol. Chem. 235: 719–25. PMID 13825299.
- Shiotani T, Weber G (1981). "Purification and properties of dihydrothymine dehydrogenase from rat liver". J. Biol. Chem. 256 (1): 219–24. PMID 7451435.
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