Dimenoxadol

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Dimenoxadol
Dimenoxadol.svg
Clinical data
Other namesDimenoxadol, Estocin
ATC code
  • none
Legal status
Legal status
Identifiers
CAS Number
PubChem CID
DrugBank
ChemSpider
UNII
ChEMBL
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC20H25NO3
Molar mass327.424 g·mol−1
3D model (JSmol)
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Dimenoxadol (INN) (brand name Estocin (in Russia)), or dimenoxadole (BAN), is an opioid analgesic which is a benzilic acid derivative, closely related to benactyzine (an anticholinergic). Further, the structure is similar to methadone and related compounds like dextropropoxyphene.

It was invented in Germany in the 1950s,[1] and produces similar effects to other opioids, including analgesia, sedation, dizziness and nausea.[2][3][4]

In the United States it is a Schedule I Narcotic controlled substance with an ACSCN of 9617 and a 2013 annual aggregate manufacturing quota of zero.

References[edit]

  1. ^ GB 716700, Boehringer A, et al., "A new and improved analgesic and process for its production", published 10/13/1954 
  2. ^ Gorbatova EN (1967). "[The pharmacology of estocin, an new analgesic]". Stomatologiia. 46 (2): 22–5. PMID 5232927.
  3. ^ Kingisepp GI, Kurvits K, Nurmand LB (1969). "[Pharmacology of dimethylaminoethyl ester of diphenylethoxyacetic acid hydrochloride--estocin]". Farmakologiia I Toksikologiia. 32 (6): 710–2. PMID 5381602.
  4. ^ Liberman SS (1968). "[Analgesic action of estocin (dimethylaminoethyl ester hydrochloride of alpha, alpha-diphenylethoxyacetic acid)]". Farmakologiia I Toksikologiia. 31 (6): 668–71. PMID 5729519.