Dimethylallyltranstransferase

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Dimethylallyltranstransferase
Identifiers
EC number 2.5.1.1
CAS number 9032-79-5
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum
farnesyl diphosphate synthase (farnesyl pyrophosphate synthetase, dimethylallyltranstransferase, geranyltranstransferase)
Identifiers
Symbol FDPS
Entrez 2224
HUGO 3631
OMIM 134629
RefSeq NM_002004
UniProt P14324
Other data
EC number 2.5.1.1
Locus Chr. 1 q22

Dimethylallyltranstransferase is an enzyme that converts dimethylallylpyrophosphate and isopentenyl pyrophosphate into farnesylpyrophosphate.[1][2] It is also referred to as farnesylpyrophosphate synthase or farnesyldiphosphate synthase.

Pyrophosphate is also involved, as both a reactant and a product. Geranylpyrophosphate is created in an intermediate step.

References[edit]

  1. ^ Banthorpe, D.V., Bucknall, G.A., Doonan, H.J., Doonan, S. and Rowan, M.G. (1976). "Biosynthesis of geraniol and nerol in cell-free extracts of Tanacetum vulgare". Phytochemistry 15: 91–100. 
  2. ^ Sagami, H., Ogura, K., Seto, S. and Kurokawa, T. (1978). "A new prenyltransferase from Micrococcus lysodeikticus". Biochem. Biophys. Res. Commun. 85: 572–578. PMID 736921. 

See also[edit]

External links[edit]