|CompTox Dashboard (EPA)|
|Chemical and physical data|
|Molar mass||205.301 g·mol−1|
|3D model (JSmol)|
Dimethylaminopivalophenone is an opioid analgesic. with a potency ½ that of morphine. It was initially discovered by Russian scientists in 1954 and subsequently rediscovered in the US in 1969. Its LD50 in mice is 83 mg/kg. It has never been marketed commercially, likely due to its low potency and lack of benefits compared to existing agents.
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- Edward F. Kleinman (April 2011). "Dimethyl(methylene)ammonium Iodide". Encyclopedia of Reagents for Organic Synthesis. E-EROS Encyclopedia of Reagents for Organic Synthesis. doi:10.1002/047084289X.rd346. ISBN 978-0471936237.
- Helmut Buschmann; Wolfgang Strassburger; Elmar Friderichs (24 January 2002). "Patent US 20020010178 - 1-phenyl-3-dimethylaminopropane compounds with a pharmacological effect". Retrieved 2 October 2015.
- Manmohan S. Atwal; Ludwig Bauer; S. N. Dixit; J. E. Gearien; M. Magahy; R. Morris; C. Pokorny (November 1969). "Analgetics. II. Relationship between structure and activity of some beta-amino ketones". Journal of Medicinal Chemistry. 12 (6): 994–997. doi:10.1021/jm00306a006. PMID 5351480.
- "2,2-dimethyl-3-(dimethylamino)-Propiophenone". ChemIDplus. Retrieved 2 October 2015.
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