Dimethylphenylpiperazinium

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Dimethylphenylpiperazinium
Identifiers
  • 1,1-Dimethyl-4-phenylpiperazin-1-ium
CAS Number
PubChem CID
ChemSpider
ChEMBL
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC12H19N2
Molar mass191.29 g/mol g·mol−1
3D model (JSmol)
  • C[N+]1(CCN(CC1)C2=CC=CC=C2)C
  • InChI=1S/C12H19N2/c1-14(2)10-8-13(9-11-14)12-6-4-3-5-7-12/h3-7H,8-11H2,1-2H3/q+1 checkY
  • Key:MKGIQRNAGSSHRV-UHFFFAOYSA-N checkY
 ☒NcheckY (what is this?)  (verify)

Dimethylphenylpiperazinium (DMPP) is a nicotinic acetylcholine receptor agonist which is selective for the ganglionic subtype.[1] One of the earliest reports on the pharmacology of DMPP, describing it as a ganglion-stimulating, hypertensive agent, came from Graham Chen and his co-workers at Parke, Davis & Co.[2]

See also

References

  1. ^ Prado WA, Segalla DK (August 2004). "Antinociceptive effects of bethanechol or dimethylphenylpiperazinium in models of phasic or incisional pain in rats". Brain Res. 1018 (2): 272–82. doi:10.1016/j.brainres.2004.05.085. PMID 15276888.
  2. ^ G. Chen, R. Portman and A. Wickel (1951) J. Pharmacol. Exp. Ther. 103 (1951).



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