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Dinoxyline structure.png
Clinical data
ATC code
  • none
PubChem CID
Chemical and physical data
Molar mass255.268 g·mol−1
3D model (JSmol)

Dinoxyline is a synthetic compound developed for scientific research, which acts as a potent full agonist at all five dopamine receptor subtypes.[1][2][3]


  1. ^ Grubbs RA, Lewis MM, Owens-Vance C, Gay EA, Jassen AK, Mailman RB, Nichols DE (March 2004). "8,9-dihydroxy-1,2,3,11b-tetrahydrochromeno[4,3,2,-de]isoquinoline (dinoxyline), a high affinity and potent agonist at all dopamine receptor isoforms". Bioorganic & Medicinal Chemistry. 12 (6): 1403–12. doi:10.1016/j.bmc.2004.01.008. PMID 15018913.
  2. ^ Ryman-Rasmussen JP, Nichols DE, Mailman RB (October 2005). "Differential activation of adenylate cyclase and receptor internalization by novel dopamine D1 receptor agonists". Molecular Pharmacology. 68 (4): 1039–48. doi:10.1124/mol.105.012153. PMID 15985612.
  3. ^ Zhang J, Xiong B, Zhen X, Zhang A (March 2009). "Dopamine D1 receptor ligands: where are we now and where are we going". Medicinal Research Reviews. 29 (2): 272–94. doi:10.1002/med.20130. PMID 18642350.