Georgije Mitrofanović (Serbian Cyrillic: Георгије Митрофановић[a]; c. 1550–c. 1630) was a Serbian Orthodox monk and painter, remembered best for his work on the Morača monastery church and the frescoes (wall paintings) inside the Krupa monastery church. Mitrofanović, a monk, had trained at the Hilandar monastery workshop, situated on Mount Athos, before coming to Montenegro where he worked on frescoes in the Morača monastery. He had many pupils and associates, but his most famous follower was Zograph Jovan.
Serbian Patriarch Pajsije initiated the restoration of the old 13th- and 14th-century churches of the Patriarchate of Peć in 1620. Its restoration marked the symbolic beginning of the renaissance of true artistic activity in the territories subordinate to prikazes of the Patriarchate of Peć. All the domes of the churches were covered with lead, the Church of St. Demetrius was practically rebuilt, and almost half of the frescoes were restored by Mitrofanović, giving them a new layer. The major part of the early 17th-century frescoes in the church is found in the altar and in the space between the cupola. Retaining the old subjects and respecting the preceding compositional solutions, Mitrofanović tended to approach the artistic attitude of master painter John's from the 14th century retaining at the same time his own warmer colouring.