They were between a Bulldog and a Mastiff in size. The muzzle was short, broad, and abruptly truncated. The head was broad and flat, and the lips, deeply pendulous. The medium-sized ears, were also partly pendulous, the tail rather short, cylindrical, and turned upwards and forwards towards the tip. They were described as a "rusty wolf-colour", with black face, lips, and legs. They were very notable for their chasing of slaves.
The Cuban Mastiff developed from several breeds of bulldogs, Mastiffs and cattle dogs becoming an ideal fighter and property guardian. It is possible that some specimens of this breed were brought to America where they were employed as watchdogs. They were also used as slave retrievers by the British during the Second Maroon War, by the French during the Saint-Domingue expedition, as well as the American in the southern States.
The breed is considered extinct since the end of the 19th century, but there have been reports which state that although no pure Dogo Cubanos remain, the dogs used in today’s fighting pits in Cuba are descendants of the crossbreed between Pit Bulls, Cordoba Bulldogs and Dogo Argentinos and the few pure Dogo Cubanos that were remaining by the beginning of the 20th century. The modern descendant of this rare dog breed is much larger and stronger than the original and resembles the American Pit Bull Terrier.