"Don't Go (Girls and Boys)" was Fefe Dobson's fourth and final single from her debut album, released in July 2004. Although it did not appear on the initial release of Fefe Dobson, the song was appended to later pressings. The song is featured in a Tommy Hilfiger commercial that starred Dobson.
The music video for "Don't Go"  was set in New York City, with references to subways, 43rd Street, and CBGB in both the song and video. The video starred Dobson and Drake Bell running away from two unidentified men in black suits and culminates with Dobson performing the song on-stage at CBGB.