Born as the son of two musicians in Plymouth, England, Rendell's jazz career began when he was fifteen, with the alto sax, switching to tenor after a few years. His earliest professional engagements were with big bands, first on U.S. bases for the U.S.O. in 1944, and then with the Oscar Rabin Band, among others. In 1950 he became a member of the Johnny Dankworth Seven, remaining until 1953. When Dankworth decided to put together a big band, Rendell parted company with him.
As well as gigging as a guest soloist around London's jazz clubs, he started to lead his own groups; from 1954 these often featured Ronnie Ross, who played tenor at that time. He also spent time working with Tony Crombie and Ted Heath, toured Europe with Stan Kenton in 1956, played with Woody Herman's Anglo-American Herd in 1959, and led a group accompanying Billie Holiday when she toured in the UK. His own groups featured musicians such as Graham Bond, Michael Garrick, Barbara Thompson, John Burch and Ian Carr. In 1963 he and Carr formed the Rendell–Carr Quintet, which performed and recorded for some seven years.
Rendell's style owed much to Lester Young, and he added many other influences during his career, including John Coltrane. He was a leading jazz-educator, and taught for the Guildhall School of Music and Drama in London from 1984.
Rendell died on 20 October 2015 in London after a short illness at the age of 89.
The dates are the original recording/release dates, the labels are the re-issue labels.
- Meet Don Rendell (1954–55: Jasmine)
- Playtime (1958: Vocalion) — reissue contains 1959 material by Jazz at the Flamingo and The Jazz Committee
- Roarin (1961: BGP)
- Shades of Blue (1964: BGO) — the Rendell–Carr Quintet
- Don Rendell Four and Five & Rendell–Carr Quintet 1964–68 (1964–68: Spotlite)
- Live in London (1965: Harkit Records) — the Rendell–Carr Quintet
- Dusk Fire (1966: BGO) — the Rendell–Carr Quintet
- Phase III (1967: BGO) — the Rendell–Carr Quintet
- Live (1968: BGO) — the Rendell–Carr Quintet
- Change Is (1969: BGO) — the Rendell–Carr Quintet
- Greek Variations (1970: impressed re-pressed) — with Neil Ardley & Ian Carr
- Space Walk (c.1972: Redial)
- Live at the Avgarde Gallery Manchester (1974: Spotlite)
- Just Music (1974: Spotlite)
- If I Should Lose You (1990–91: Spotlite) — Don Rendell and his Big 8
- What Am I Here For? (1993–96: Spotlite)
- Reunion: Don Rendell with Ian Carr & Michael Garrick (2002: Spotlite)
- Live in London (2003: Harkit) — the Don Rendell–Ian Carr Quintet