Doramectin

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Doramectin
Doramectin.svg
Doramectin2.png
Clinical data
AHFS/Drugs.com International Drug Names
Routes of
administration
Injection, Topical and Oral
ATCvet code
Legal status
Legal status
  • Veterinary use only
Identifiers
CAS Number
PubChem CID
ChemSpider
UNII
KEGG
ECHA InfoCard 100.123.125
Chemical and physical data
Formula C50H74O14
Molar mass 899.114
  (verify)

Doramectin (Dectomax) is a veterinary drug approved by the Food and Drug Administration (FDA) for the treatment of parasites such as gastrointestinal roundworms, lungworms, eyeworms, grubs, sucking lice and mange mites in cattle.[1]

It is used for the treatment and control of internal parasitosis (gastrointestinal and pulmonary nematodes), ticks and mange (and other ectoparasites). Doramectin is a derivative of ivermectin. Its spectrum includes: Haemonchus, Ostertagia, Trichostrongylus, Cooperia, and Oesophagostomum species and Dictyocaulus viviparus, Dermatobia hominis, Boophilus microplus, and Psoroptes bovis, among many other internal and external parasites. It is available as an injection and as a 5-mg/ml topical solution.

Doramectin is also marketed in many Latin-American and some Asia and Africa countries as Doramec L.A. (manufactured by Agrovet Market Animal Health[2]) in an 1% Doramectin Long Acting Injectable Solution for cattle, sheep, swine[3] and others. Its oleous carrier confers to Doramec L.A. a slow and prolonged liberation, extending its action up to 42 days.

Doramectin is also available for horses[3] as an oral, flavored, bioadhesive gel under the name Doraquest L.A. Oral Gel.[4] It can be used to control and treat internal parasites as roundworms, lungworms and some external parasites.

References[edit]