In 1966, Brown became the first woman to run a sub-5 minute mile indoors, clocking 4:52. At one point in her career she held every women’s national and world record from 440 yards up through one mile. Brown is perhaps best remembered for her five victories in the International Cross Country Championships (1967–1971), and she also represented the United States at the 1968 and 1972 Olympics games. In 1976, Brown won the Vancouver International Marathon and placed second in the New York City Marathon. She coached track and cross country at Seattle Pacific University for four decades.