|Topical (eye drops)|
|Elimination half-life||4 months|
|Chemical and physical data|
|Molar mass||324.443 g/mol g·mol−1|
|3D model (JSmol)|
|(what is this?)|
Dorzolamide (trade name Trusopt) is a carbonic anhydrase inhibitor. It is an anti-glaucoma agent, and acts by decreasing the production of aqueous humour. It is administered as a topical ophthalmic in the form of a 2% solution.
In 2016 it was the 271st most prescribed medication in the United States with more than a million prescriptions.
This drug, developed by Merck, was the first drug in human therapy (market introduction 1995) that resulted from structure-based drug design. It was developed to circumvent the systemic side effects of acetazolamide which has to be taken orally.
This section needs expansion. You can help by adding to it. (January 2019)
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