Douglas Scott Falconer
Douglas Scott Falconer | |
|---|---|
| Born | 10 March 1913 Old Meldrum, Aberdeenshire, Scotland |
| Died | 23 February 2004 (aged 90) Edinburgh, Scotland |
| Alma mater | University of St Andrews King's College, Cambridge |
| Scientific career | |
| Fields | Quantitative genetics Genetic epidemiology |
| Institutions | Edinburgh University |
| Doctoral advisor | James Gray |
Douglas Scott Falconer FRS FRSE (10 March 1913 in Oldmeldrum, Aberdeenshire – 23 February 2004 in Edinburgh)[1] was a Scottish geneticist known for his work in quantitative genetics.[2] Falconer's book Introduction to quantitative genetics was written in 1960 and became a valuable reference for generations of scientists. Its latest edition dates back to 1996 and is coauthored by Trudy Mackay.[3]
In 1951, Falconer described a novel mouse mutant that he called reeler for its peculiar gait.[4] Later research using these mice has led to the discovery of reelin, a protein playing important roles in corticogenesis, neuronal migration, and plasticity.
In 1964, he introduced the use of liability threshold models into human disease & trait modeling.[5][6]
See also[edit]
References[edit]
- ^ Bowman, J. C. (2005). "Douglas Scott Falconer. 10 March 1913 – 23 February 2004: Elected F.R.S. 1973". Biographical Memoirs of Fellows of the Royal Society. 51: 119. doi:10.1098/rsbm.2005.0008.
- ^ MacKay, T. F. C. (2004). "Douglas Scott Falconer (1913–2004)". Heredity. 93 (2): 119–121. doi:10.1038/sj.hdy.6800506. PMID 15241449.
- ^ Hill, W. G.; MacKay, T. F. (2004). "D. S. Falconer and Introduction to quantitative genetics". Genetics. 167 (4): 1529–1536. PMC 1471025. PMID 15342495.
- ^ Falconer, D. S. (1951). "Two new mutants, 'trembler' and 'reeler', with neurological actions in the house mouse (Mus musculus L.)". Journal of Genetics. 50 (2): 192–205. doi:10.1007/BF02996215.
- ^ "The inheritance of liability to certain diseases, estimated from the incidence among relatives", Falconer 1965
- ^ "The inheritance of liability to diseases with variable age of onset, with particular reference to diabetes mellitus", Falconer 1967
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- 1913 births
- 2004 deaths
- Alumni of the University of St Andrews
- Alumni of King's College, Cambridge
- Scottish geneticists
- Fellows of the Royal Society
- Fellows of the Royal Society of Edinburgh
- People from Aberdeenshire
- Academics of the University of Edinburgh
- Genetic epidemiologists
- Scottish scientist stubs
- Geneticist and evolutionary biologist stubs
