Down Sign may refer to:
- Download, to receive data to a local system from a remote system
- Keyboard key, a button on a computer keyboard, programmed to move the cursor in a down direction
- Thumbs down, a common hand gesture to denote disapproval or dislike
- logical NOR
- Sign, an object, quality, or event whose presence or occurrence indicates the presence or occurrence of something else
- Relative direction, a downward direction
- Down (Game theory), a mathematical game
- Downgrade, reverting software (or hardware) back to an older version; downgrade is the opposite of upgrade
- Downlink, signals coming down from a satellite, spacecraft, or aircraft (Down signals)
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