Meyer was the Rangers' first round pick in the 2002 Major League Baseball Draft. Meyer hit .214 in his limited major league at-bats in 2006, before he was returned to Triple-A Oklahoma, where he batted .228/.278/.305. Meyer was designated for assignment by the Texas Rangers on January 12, 2007, and was outrighted to the minor leagues after passing through league-wide waivers on January 22. As this was Meyer's first outright, he did not have the right to decline the assignment. He was also given a non-roster invitation to spring training to compete for a spot on the major league roster. He became a free agent at the end of the season and signed a minor league contract with the Houston Astros.
In 2011, Meyer returned to the University of South Carolina to complete his degree and serve as a student-assistant coach of the Gamecock baseball program. As of 2015 Meyer lives in Greenville, SC with his wife and son. He works for an insurance company.