Duncan Odom

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Duncan Odom
Born Duncan T. Odom
Alma mater
Scientific career
Thesis The application of metallointercalators in recognition of and charge transport in nucleic acids (2001)
Doctoral advisor Jacqueline Barton[5]
Other academic advisors Richard A. Young[6]
Website www.cruk.cam.ac.uk/users/duncan-odom

Duncan T. Odom is a research group leader at the Cancer Research UK Cambridge Institute (CRUK CI) at the University of Cambridge[3][6] and was an associate faculty member at the Wellcome Trust Sanger Institute between 2011-2018.[4]


Odom was educated at the New College of Florida where he was awarded a Bachelor of Arts degree in Chemistry in 1995.[4] He continued his study at California Institute of Technology (Caltech) where he was awarded a PhD in chemical engineering for research on DNA-binding metallo-intercalators supervised by Jacqueline Barton.[6][5]

Career and research[edit]

After a period as a postdoctoral researcher[7] in genetics and genomics at the Whitehead Institute in Cambridge, Massachusetts with Richard A. Young,[4] he established his research group at the University of Cambridge in 2006.[6] His research investigates how transcription and transcriptional regulation vary during evolution, and its implications for diseases such as cancer, using high throughput biology methods to investigate genome evolution.[8][9][10][11] As of 2017, according to Google Scholar his most highly-cited papers have been published in Cell,[12] Chemical Reviews,[13] and Science.[14][15]

His research has been funded by the National Institute of Diabetes and Digestive and Kidney Diseases,[6] the Alfred P. Sloan Foundation, the European Research Council, the European Molecular Biology Organization (EMBO), the Wellcome Trust[16] and Cancer Research UK.[6]

Awards and honours[edit]

Odom was awarded the Francis Crick Medal and Lecture in 2014[1][17] for his “pioneering work in the field of comparative functional genomics, which has changed our understanding of the evolution of mammalian transcriptional regulation.”[1] He was awarded EMBO Membership in 2015[2], and the Mary Lyon Medal from the Genetics Society (UK) in 2016.[18]


  1. ^ a b c Anon (2014). "Crick Lecture: Genetic control and the mammalian radiation". royalsociety.org. London: Royal Society. Archived from the original on 2017-05-03. 
  2. ^ a b Anon (2015). "Duncan T. Odom". people.embo.org. Heidelberg: European Molecular Biology Organization. 
  3. ^ a b Duncan Odom publications indexed by Google Scholar Edit this at Wikidata
  4. ^ a b c d Anon (2016). "Dr Duncan Odom: Associate Faculty". sanger.ac.uk. Wellcome Trust. Archived from the original on 2016-09-07. 
  5. ^ a b Odom, Duncan T. (2001). The application of metallointercalators in recognition of and charge transport in nucleic acids. proquest.com (PhD thesis). California Institute of Technology. OCLC 874759941. 
  6. ^ a b c d e f Duncan Odom Entry at ORCID
  7. ^ Odom, D. T. (2014). "Survival strategies for choosing the right postdoc position". Genome Biology. 15 (3): 107. doi:10.1186/gb4163. PMC 4053951Freely accessible. PMID 25001498.  open access publication – free to read
  8. ^ Odom, Duncan (2017). "Odom group: Transcription Regulation Laboratory". cruk.cam.ac.uk. Archived from the original on 2017-02-07. 
  9. ^ Villar, Diego; Berthelot, Camille; Aldridge, Sarah; Rayner, Tim F.; Lukk, Margus; Pignatelli, Miguel; Park, Thomas J.; Deaville, Robert; Erichsen, Jonathan T.; Jasinska, Anna J.; Turner, James M.A.; Bertelsen, Mads F.; Murchison, Elizabeth P.; Flicek, Paul; Odom, Duncan T. (2015). "Enhancer Evolution across 20 Mammalian Species". Cell. 160 (3): 554–566. doi:10.1016/j.cell.2015.01.006. ISSN 0092-8674. 
  10. ^ Stefflova, Klara; Thybert, David; Wilson, Michael D.; Streeter, Ian; Aleksic, Jelena; Karagianni, Panagiota; Brazma, Alvis; Adams, David J.; Talianidis, Iannis; Marioni, John C.; Flicek, Paul; Odom, Duncan T. (2013). "Cooperativity and Rapid Evolution of Cobound Transcription Factors in Closely Related Mammals". Cell. 154 (3): 530–540. doi:10.1016/j.cell.2013.07.007. ISSN 0092-8674. PMC 3732390Freely accessible. PMID 23911320.  open access publication – free to read
  11. ^ Ernst, Christina; Pike, Jeremy; Aitken, Sarah J; Long, Hannah K; Eling, Nils; Stojic, Lovorka; Ward, Michelle C; Connor, Frances; Rayner, Timothy F; Lukk, Margus; Klose, Robert J; Kutter, Claudia; Odom, Duncan T (2016). "Successful transmission and transcriptional deployment of a human chromosome via mouse male meiosis". eLife. 5. doi:10.7554/eLife.20235. ISSN 2050-084X. PMC 5161449Freely accessible. PMID 27855777.  open access publication – free to read
  12. ^ Lee, Tong Ihn; Jenner, Richard G.; Boyer, Laurie A.; Guenther, Matthew G.; Levine, Stuart S.; Kumar, Roshan M.; Chevalier, Brett; Johnstone, Sarah E.; Cole, Megan F.; Isono, Kyo-ichi; Koseki, Haruhiko; Fuchikami, Takuya; Abe, Kuniya; Murray, Heather L.; Zucker, Jacob P.; Yuan, Bingbing; Bell, George W.; Herbolsheimer, Elizabeth; Hannett, Nancy M.; Sun, Kaiming; Odom, Duncan T.; Otte, Arie P.; Volkert, Thomas L.; Bartel, David P.; Melton, Douglas A.; Gifford, David K.; Jaenisch, Rudolf; Young, Richard A. (2006). "Control of Developmental Regulators by Polycomb in Human Embryonic Stem Cells". Cell. 125 (2): 301–313. doi:10.1016/j.cell.2006.02.043. ISSN 0092-8674. PMC 3773330Freely accessible. PMID 16630818.  open access publication – free to read
  13. ^ Erkkila, Kathryn E.; Odom, Duncan T.; Barton, Jacqueline K. (1999). "Recognition and Reaction of Metallointercalators with DNA". Chemical Reviews. 99 (9): 2777–2796. doi:10.1021/cr9804341. ISSN 0009-2665. 
  14. ^ Lee, T. I. (2002). "Transcriptional Regulatory Networks in Saccharomyces cerevisiae". Science. 298 (5594): 799–804. doi:10.1126/science.1075090. ISSN 0036-8075. PMID 12399584. 
  15. ^ Odom, D. T. (2004). "Control of Pancreas and Liver Gene Expression by HNF Transcription Factors". Science. 303 (5662): 1378–1381. doi:10.1126/science.1089769. ISSN 0036-8075. PMC 3012624Freely accessible. PMID 14988562.  open access publication – free to read
  16. ^ Anon (2017). "Investigator Awards in Science: people we've funded". wellcome.ac.uk. Wellcome Trust. Archived from the original on 2017-04-26. 
  17. ^ Event video: Genetic control and the mammalian radiation on YouTube
  18. ^ http://www.genetics.org.uk/medals-and-prizes/2015-winners/mary-lyon-medal/