EA-2012

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EA-2012
Chemical structure of the EA-2012.png
Names
Preferred IUPAC name
Bis(tetraphenylboranuide) N,N,N-trimethyl-3-({[(propan-2-yl)oxy](methylphosphonoyl)}oxy)-5-{4-[3-(trimethylazaniumyl)phenoxy]butoxy}anilinium
Identifiers
3D model (JSmol)
  • InChI=1S/C26H43N2O5P.2C24H20B/c1-21(2)32-34(9,29)33-26-19-23(28(6,7)8)18-25(20-26)31-16-11-10-15-30-24-14-12-13-22(17-24)27(3,4)5;2*1-5-13-21(14-6-1)25(22-15-7-2-8-16-22,23-17-9-3-10-18-23)24-19-11-4-12-20-24/h12-14,17-21H,10-11,15-16H2,1-9H3;2*1-20H/q+2;2*-1
    Key: UBOLPSQXNCTHEF-UHFFFAOYSA-N
  • [B-](c1ccccc1)(c2ccccc2)(c3ccccc3)c4ccccc4.[B-](c1ccccc1)(c2ccccc2)(c3ccccc3)c4ccccc4.CC(C)OP(=O)(C)Oc5cc([N+](C)(C)C)cc(c5)OCCCCOc6cccc(c6)[N+](C)(C)C
Properties
C74H83B2N2O5P
Molar mass 1133.08 g·mol−1
Appearance Solid
Melting point 171–172 °C (340–342 °F; 444–445 K)
Insoluble
Solubility Soluble in acetone
Hazards
Occupational safety and health (OHS/OSH):
Main hazards
Extremely toxic
Lethal dose or concentration (LD, LC):
93 μg/kg (Rats, IV)
17 μg/kg (Rabbits, IV)
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).

EA-2012 is an extremely toxic organophosphate nerve agent. It's an extremely potent acetylcholinesterase inhibitor that is resistant to atropine and oxime treatment.[1]

See also[edit]

References[edit]

  1. ^ "Toxic phosphorus compounds".