Acetylenedicarboxylate decarboxylase

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Acetylenedicarboxylate decarboxylase
Identifiers
EC number 4.1.1.78
CAS number 72561-10-5
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum
Gene Ontology AmiGO / QuickGO

In enzymology, an acetylenedicarboxylate decarboxylase (EC 4.1.1.78) is an enzyme that catalyzes the chemical reaction

acetylenedicarboxylate + H2O pyruvate + CO2

Thus, the two substrates of this enzyme are acetylenedicarboxylate and H2O, whereas its two products are pyruvate and CO2.

This enzyme belongs to the family of lyases, specifically the carboxy-lyases, which cleave carbon-carbon bonds. The systematic name of this enzyme class is acetylenedicarboxylate carboxy-lyase (pyruvate-forming). Other names in common use include acetylenedicarboxylate hydratase, acetylenedicarboxylate hydrase, and acetylenedicarboxylate carboxy-lyase. This enzyme participates in pyruvate metabolism.

References[edit]

  • Yamada EW; Jakoby WB (1958). "Enzymatic utilization of acetylenic compounds. I. An enzyme converting acetylenedicarboxylic acid to pyruvate". J. Biol. Chem. 233 (3): 706–711. PMID 13575441.