Acetylenecarboxylate hydratase

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acetylenecarboxylate hydratase producing 3-oxopropanoate
Identifiers
EC number 4.2.1.27
CAS number 9024-26-4
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum
Gene Ontology AmiGO / QuickGO

In enzymology, an acetylenecarboxylate hydratase (EC 4.2.1.27) is an enzyme that catalyzes the chemical reaction

3-oxopropanoate propynoate + H2O

Hence, this enzyme has one substrate, 3-oxopropanoate, and two products, propynoate and H2O.

This enzyme belongs to the family of lyases, specifically the hydro-lyases, which cleave carbon-oxygen bonds. The systematic name of this enzyme class is 3-oxopropanoate hydro-lyase (propynoate-forming). Other names in common use include acetylenemonocarboxylate hydratase, alkynoate hydratase, acetylenemonocarboxylate hydrase, acetylenemonocarboxylic acid hydrase, malonate-semialdehyde dehydratase, and 3-oxopropanoate hydro-lyase. This enzyme participates in 3 metabolic pathways: beta-alanine metabolism, propanoate metabolism, and butanoate metabolism.

References[edit]

  • Probst C, Grotz M, Krettek C, Pape HC (2005). "Impact of hypothermia on the immunologic response after trauma and elective surgery". Surg. Technol. Int. 14: 41–50. PMID 16525953. 
  • YAMADA EW, JAKOBY WB (1959). "Enzymatic utilization of acetylenic compounds. II Acetylenemonocarboxylic acid hydrase". J. Biol. Chem. 234 (4): 941–5. PMID 13654296.