Endothelin 2

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EDN2
Identifiers
Aliases EDN2, ET2, PPET2, ET-2, endothelin 2
External IDs MGI: 95284 HomoloGene: 1477 GeneCards: 1907
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001956
NM_001302269

NM_007902

RefSeq (protein)

NP_001289198.1
NP_001947.1

NP_031928.2

Location (UCSC) Chr 1: 41.48 – 41.48 Mb Chr 4: 120.16 – 120.17 Mb
PubMed search [1] [2]
Wikidata
View/Edit Human View/Edit Mouse

Endothelin 2, also known as ET-2, is a protein that in humans is encoded by the EDN2 gene.[1]

Function[edit]

Endothelin 2 is a member of the endothelin protein family of secretory vasoconstrictive peptides. The preproprotein is processed to a short mature form which functions as a ligand for the endothelin receptors that initiate intracellular signaling events. This gene product is involved in a wide range of biological processes, such as hypertension and ovulation.[1]

References[edit]

Further reading[edit]