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eEF-1 is a eukaryotic elongation factor.

Its α and βγ subunits act as counterparts to EF-Tu and EF-Ts, respectively

Genes include:

Various species of green algae, red algae, chromalveolates, and fungi lack the EF-1α gene but instead possess a related gene called EFL (elongation factor-like). Although its function has not been studied in depth, it appears to be similar to EF-1α.

Only two organisms are known to have both EF-1α and EFL: the fungus Basidiobolus and the diatom Thalassiosira. The evolutionary history of EFL is unclear. It may have arisen one or more times followed by loss of EFL or EF-1α. The presence in three diverse eukaryotic groups (fungi, chromalveolates, and archaeplastida) is supposed to be the result of two or more horizontal gene transfer events.[1]

See also[edit]


  1. ^ Ellen Cocquyt; Heroen Verbruggen; Frederik Leliaert; Frederick W Zechman; Koen Sabbe; Olivier De Clerck (2009), "Gain and loss of elongation factor genes in green algae", BMC Evol. Biol., 9: 39, doi:10.1186/1471-2148-9-39, PMC 2652445, PMID 19216746

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